Publication: American Journal of Veterinary Research,
December 1999
Title: “Evaluation of Glucosamine HCI and Chondroitin
Sulfate as Treatment for Acute Synovitis in Dogs - In this
study, within 48 days dogs had shown signs of significantly
less inflammation after using Glucosamine HCL and
Chondroitin Sulfate. The authors concluded that Glucosamine
and Chondroitin administration prior to joint insult had a
protective effect against synovitis and bone remodeling.
Publication: Veterinary
Orthopedic Society, 25th Annual Conference, February
1998
In this study, the authors concluded that Glucosamine and
Chondroitin for dogs had two primary effects: a reduction in the
severity of cartilage breakdown in the operated joints, and
a return of the repaired joint to a more normal physiologic
state.
Publication: Alternative Medicine Review, Jun 1999
Glucosamine sulfate's role in halting or reversing joint
degeneration appears to be directly due to its ability to
act as an essential substrate for, and to stimulate the
biosynthesis of, the glycosaminoglycans and the hyaluronic
acid backbone needed for the formation of the proteoglycans
found in the structural matrix of joints. Successful
treatment of osteoarthritis must effectively control pain
and should slow down or reverse the progression of the
degeneration. Biochemical and pharmacological data combined
with animal, dog and human studies demonstrate that
glucosamine sulfate is capable of satisfying both of these
criteria.